Here you can visualize, access, explore, filter, and download the serum metabolome data from the REM-HF cohort.
Please refer to Pietzner M et al (doi: 10.1038/s41591-021-01266-0) and Murthy VL et al (doi: 10.1001/jamacardio.2020.2686) for the EPIC-Norfolk and BPRHS cohorts, respectively.
- H in the first panel indicates CHF-specific metabolites; D, T2D specific; and K, CKD specific.
- Pathway annotations for different metabolites in the boxplot panel were highlighted in different colors.
- HMDB and KEGG links for each metabolite were embedded in the mouseover tooltips.
- 'Explained variance' indicates the explained variance (ranging from 0 to 1) for each metabolite by all obtained clinical variables based on random forest regression.
- The hazard ratio (HR) for mortality or chronic heart failure (CHF) rehospitalization was calculated using Cox proportional hazards model adjusting for age, sex and BMI.